HLA B27 - What is the significance of HLA B27 in rheumatic disease?HLA B27 is an inherited gene marker associated with a number of related rheumatic diseases.HLA-B27-Associated Reactive Arthritis: Pathogenetic and Clinical ...Current evidence supports the concept that reactive arthritis (ReA) is an immune-mediated synovitis resulting from slow bacterial infections and showing intra ...HLA-B27 Syndromes - Diseases & Conditions - Medscape ReferenceHLA-B27 is associated with the pustular form of psoriasis, and the association of HLA-B27 in peripheral psoriatic arthritis is weak. In the presence of ...