CPPD (Calcium Pyrophosphate Dihydrate Deposition Disease) - What ...CPPD (calcium pyrophosphate dihydrate deposition disease) is a type of arthritis caused by deposits of calcium phosphate crystals in joints. CPPD is also ...Arthritis Disease Center l Disease Definitions l Arthritis Disease ...What is it? Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease occurs when these crystals collect in joints and the tissues surrounding the joints.Chondrocalcinosis - Wikipedia, the free encyclopediaCPPD crystal deposition disease is a polyarticular arthritis (i.e., it leads to an inflammation of several joints in the body), although it may begin as monoarticular (i ...